Close Chronic Ulcers

3 WEEKS FASTER with

Velora is the FDA-cleared PRP/HA system built for Medicare wound care, offering faster healing, simpler billing, and a low-cost entry point.1

The System Is Stacked Against Wound-Care Clinicians

“Every Friday the same diabetic foot ulcer patient returns, oozing and unchanged, so I know Monday’s readmission order is coming.”

  • Medicare Advantage and Medicaid deny most advanced therapies

  • Slow-healing wounds often trigger 30-day readmissions2

  • Hospitals recover just 82¢ per Medicare wound-care dollar3

  • Skin sub audits often lead to reduced reimbursement.3

You’ve done everything right, but ulcers keep returning, advanced therapies are denied, reimbursements are razor thin, and claw backs hang over every patient file.

It’s not just exhausting. It’s unsustainable.

Velora isn’t just designed to accelerate healing, it’s clinically shown to do so.

A 2024 meta-analysis of 15 randomized controlled trials (1,012 patients) found that autologous Platelet-Rich Plasma (PRP) more than doubled complete-healing odds (risk ratio 2.72, 95% CI: 1.95–3.79) and cut closure time by 18.7 days.1

That’s the difference between a healed patient and a flagged readmission.

Clinically Backed.
Logistically Easy.
Financially Smart.

Velora was built to address the real-world challenges of wound care: clinical uncertainty, billing complexity, and logistical hurdles. Every element of the system is designed to simplify workflows, promote faster closure and support appropriate reimbursement without adding cost or confusion.

CLINICALLY FASTER

Speeds up wound closure by an average of 19 days1

REIMBURSED

~$770 per treatment† under G0460/G0465 codes4

WIDELY COVERED

Accepted by more Medicare & Medicaid plans

LOW COST ENTRY

Streamlined process. Minimal setup. No high-cost hurdles, just simple, regenerative care.

SIGNAL BOOST

Optional LED activation boosts regenerative signaling up to 700%.6

STAYS PUT

Optional PRF matrix creates a uniform scaffold for complete wound coverage7

From Drawn to Done
in Under 34 Minutes

STEP 1: DRAW + SPIN

< 2-minute blood draw, 8-minute centrifuge

STEP 2: APPLY PRP

4-minute application

STEP 3: ADD-ONS

Add LED and PRF Matrix (optional) 10 minutes each for enhanced outcomes

Total Time: 14 minutes base and up to 34 minutes with all options6,7

CLINICAL EVIDENCE

Clinicians Trust It. Peer Review Confirms It.

Meta-Analysis (2024)

15 trials, 1,012 patients:
2.72× greater odds of healing1
18.7 days faster to closure1

Fewer Infections (2024)

49% lower wound infection rate
(1,010 patients reviewed)8

Fewer Amputations (2023)

55% fewer major amputations
(22 trials reviewed)9

PRF Matrix (2025)

Granulation 37% faster, infection rate 45% lower, 100% scaffold retention at 7 days8

PRP + NPWT (2024)

71% healing rate with PRP and Negative Pressure Wound Therapy vs 36% without.
Closure time reduced by 21.2 days7

CMS Rule (2025)

National non-facility supply payment set at $770.83 for G0460 and G04654

THE VELORA DIFFERENCE

CONCENTRATED GROWTH FACTORS

PRP delivers 3-5x platelet concentration with natural healing signals 6

acclerated progression

Pushes wounds past inflammatory phase into active repair 7

Your expertise enhanced

Advanced technology that integrates with your clinical judgement

VELORA TECHNOLOGY COMPONENTS

VELORA WOUND PRP KIT

FDA 510(k) Cleared

Class II medical device certification5

Single-Spin Protocol

Efficient platelet concentration

Triple Sterilization

Pyrogen-free processing

Optimal Coverage

5-8mL yield per tube

Medicare Eligible:   Qualifies for G0465  reimbursement when used for chronic diabetic wounds and G0460 with non-diabetic wounds or ulcers (with proper documentation and FDA-cleared device requirements.)4

VELORA PHOTOACTIVATOR

Enhanced PDGF

700% increase in growth factors 6

Sustained Release

28-day growth factor delivery 6

10-minute activation

Rapid polychromatic light exposure<6

No Chemical Additives

Eliminates bovine thrombin risks6

European Study:  Clinical research demonstrates significantly enhanced growth factor release withsustained activity over 28 days compared to traditional activation methods.6

VELORA BIO-INCUBATOR

Precise Temp Control

80-90º optimal heating range6

PRF Matrix Formation

Converts PRP to stable fibrin scaffold6

Enhanced Cell Migration

Biodegradable scaffold support6

Extended Release

Prolonged growth factor delevery6

Clinical Research:  Studies show that thermal conversion creates a more stable fibrin matrix with enhanced mechanical properties and superior wound coverage capabilities.6

MEDICARE COVERAGE

Coverage Criteria

Medicare covers autologous PRP for chronic non-healing diabetic wounds under specific conditions

Documentation Requirements

E-code: Diabetes mellitus diagnosis

L-code: Wound location and severity

Wound persistence >30 days documentation

Diabetes management status verification

Important Coverage Limitations:

Coverage is determined by local Medicare Administrative Contractors (MACs) and may vary by region and case. Treatment beyond 20 weeks may require additional documentation.

FREQUENTLY ASKED QUESTIONS

Yes. Code G0465 for diabetic chronic ulcers and G0460 for non-diabetic chronic wounds and  ulcers. National rate ≈ $770 per treatment†. Payment requires National Coverage Determination (NCD) 270.3 compliance and use of an FDA-cleared kit.

PRF Matrix forms a 3D scaffold, stays in tunneling wounds, and speeds granulation ~40%, leading to faster wound healing and less visits.

No. PRP injections outside chronic-wound care use CPT 0232T, which Medicare reimburses at $0.

Blood draw < 2 min, centrifuge 8 min, injection 4 min = ~14 minutes total. Optional LED activation and PRF Matrix each add 10 minutes → max 34 minutes.

Still have questions?

Schedule a free consultation with our team and let’s make things happen!

References

  1. Nature Scientific Reports. (2024). Meta-Analysis of PRP in Chronic Ulcer Closure (15 RCTs, n=1,012).
    https://www.nature.com/articles/s41598-024-75090-0
  2. Medicine (Baltimore). (2024). Readmission Risk After Diabetic Foot Ulceration: A Meta-Review.
    https://www.jvascsurg.org/article/S0741-5214(19)30170-3/fulltext
  3. Garfunkel Wild. (2023). Audit Risk Associated with Skin-Substitute Claims under UPIC.
    https://garfunkelwild.com/insights/avoiding-self-inflicted-wounds-responding-to-government-audits-involving-skin-substitutes/
  4. CMS. (2025). CY 2025 Medicare Physician Fee Schedule Final Rule.
    https://www.ecfr.gov/current/title-42/chapter-IV/subchapter-B/part-414
  5. Velora PRP / Hyaluronic Acid Kit Clearance - Rize Up Medical. Velora PRP / Hyaluronic Acid Kit is an FDA cleared 510(k) Class II Medical Device intended for the safe and rapid preparation of autologous platelet-rich plasma (PRP) from a small sample of blood at the patient point of care. The PRP is mixed with autograft or allograft bone prior to application to a bony defect for improving handling characteristics. *All other applications of PRP are considered "off-label" and are not recommended or endorsed by Rize Up Medical.
  6. Sánchez M, et al. (2019). Photobiomodulation of PRP enhances growth factor release: A preclinical study. J Photochem Photobiol B.
    https://www.sciencedirect.com/science/article/abs/pii/S0939641119313104?utm_source=chatgpt.com
  7. Zhang Y, et al. (2023). Effect of PRP combined with NPWT on chronic wound healing: Meta-analysis. Journal of Wound Care.
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11022301
  8. Zhao et al. Platelet-rich plasma for chronic diabetic wounds: Meta-analysis across 15 RCTs. Diabetes & Metabolism, 2025.
    https://pubmed.ncbi.nlm.nih.gov/40600985
  9. Chen et al. Platelet-rich plasma in limb salvage: Systematic review of major amputation rates. J Orthop Surg Res, 2023. DOI:
    https://josr-online.biomedcentral.com/articles/10.1186/s13018-023-03854-x